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MOTS-C

$169.00

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a mitochondrial-derived peptide composed of 16 amino acids. It plays a key role in regulating metabolism, cellular stress response, and mitochondrial function. Unlike most peptides, MOTS-c is encoded in the mitochondrial DNA, not nuclear DNA, making it uniquely positioned in cellular energy management and metabolic regulation.

Potential Benefits (Based on Existing Research)

MOTS-c has been studied for its potential to:

  • Improve metabolic function and insulin sensitivity
  • Support weight management and fat utilization
  • Enhance mitochondrial performance and ATP production
  • Promote exercise endurance and physical performance
  • Reduce oxidative stress and promote healthy aging
  • Offer protection against age-related metabolic decline

Note: These effects are based on preclinical research and limited human trials; MOTS-c is not FDA-approved.

SKU: HW100103 Category:

Description

Mechanism of Action

MOTS-c works by:

  • Activating AMPK (AMP-activated protein kinase), a key energy sensor in cells
  • Promoting glucose metabolism and increasing mitochondrial biogenesis
  • Enhancing fatty acid oxidation and reducing fat accumulation
  • Helping cells adapt to metabolic stress and low-energy states

Potential Side Effects / Considerations

  • Generally well-tolerated in animal and early-stage human research
  • Possible mild fatigue or appetite suppression
  • Long-term safety data is still being developed
  • Not recommended during pregnancy or for individuals with mitochondrial disorders without clinical oversight

Note: These effects are based on preclinical research and limited human trials; MOTS-c is not FDA-approved.

Additional information

Chemical Information

Full Name: Mitochondrial Open Reading Frame of the 12S rRNA Type-c (MOTS-c)
Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Molecular Formula: C₁₄₀H₂₂₄N₄₂O₃₇S₂
Molecular Weight: 2177.57 g/mol

Size

30ml

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